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Beware toast
Plus growing proof that the microbiome shapes aging, for better or worse

Issue 48 | February 28, 2025

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Happy Friday!
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In todayās issue:
Beware toast
New microbiome, younger you
Leaving the peanut-free table
and moreā¦
We love to hear from youāour community. Please share your feedback, stories, questions, testimonials, ideas, and more with us at [email protected].
šļøāšØļøSPOTLIGHT
Beware toast
The common breakfast staple and your risk of stroke.

image credit: freepik
š Toast can be a delicious and nutritious way to start your morningāespecially when topped with heart-healthy avocado or omega-rich nut butter. However, a recent study shows that toast, coffee, and other traditional breakfast foods may have traces of acrylamide, a neurotoxin and probable cancer-causing compound.
Acrylamide may increase the risk of heart attack or stroke by 60%.
Acylamide formation
The food contaminant forms during high-temperature cooking, specifically during a process called the Maillard reactionāthis occurs when sugars in carbohydrates react with proteins.
Higher cooking temperatures + longer cook time = greater risk of acrylamide formation
Isnāt all toasted or cooked food bad then?
No. The toxin is more likely to form in starchy foods which are baked, fried, or roasted. š§Ø āIf food is burnt to a crisp, it contains more acrylamide compared to a non-burnt starchy food,ā according to Eating Well. While some organizations also have concerns about its risk of cancer, Thereās not consistent evidence that shows it causes cancer.
So before you give up toastā¦
Toast it less for a safer solution, and consider that most things are not harmful in moderationāincluding eating burnt food, according to expert Eva De Angelis, LDN in Eating Well.
LIVE MORE+
š„ The pickled avocado toast upgrade you should try. Read more.
š„¦ Sulfer-containing compounds reduce acylamide formation in cooking. Hereās how.
š³ The best way to cook eggs for taste, texture, and health. Read more.
Be part of the action
Apply to showcase your product or service today. Contact [email protected] to learn how you can be part of The Livelong Experience.

WELLNESS WATCH - Gut health + aging
A new microbiome can make you younger, or it ages you

image credit: freepik
A growing body of research offers proof that the microbiomeāthe collection of microorganisms that live in and on our bodiesācontributes to aging and disease, according to Dr. Michael Greger in a new video.
For better or worse: A new microbiome reshapes health
In one study, young fruit flies got something similar to a fecal transplant, and the donors were older flies.
Feces contain the microbiome of an organism, and transplants can be used to observe how the microbiome impacts aging
After receiving an older microbiome, the younger flies experienced:
Inflammation
Intestinal permeability (āleaky gutā)
Reduced health span
Earlier death
A similar trend emerged when feces from an old mouse were given to a young, germ-free mouse.
On the other hand, older African turquoise killifish were shown to live longer and healthier when their microbiomes were recolonized with those of younger fish.š
Similarly, germ-free rodents who got gut flora from the longest-living humans had less aging pigments in the brain. š§
Other fascinating bits
Antibiotics increased lifespan in the fruit flies, the suspected reason being they kill ābad bugsā in the older microbiome that drive inflammation and leaky gut.
Disease may transfer through gut bugs. Numerous studies have found that fecal transplants from diseased mice into microbe-free mice are a medium for transferring disease.
Big picture
Based on analysis from these studies, Greger suggests that:
Lifespan may be determined by āgut leakinessā
The microbiome can have a functional role in aging
The lethal aging combination = aged immune system + an aged microbiome
IN OTHER NEWS
Combat stress-induced eating with a microbiome diet

Eating a microbiome diet may prevent stress eating by boosting healthy gut bugs linked with less food addition and binge eating, according to an article in Psychology Today.
š Prolonged stress + bad microbes impact hormones that make you crave high-calorie/sugary foods. This creates a āviciousā cycle between the gut and brain.
This cycle stresses your regulatory systems and can lead to metabolic dysregulation, obesity, insulin resistance, and cardiovascular disease, say microbiome researchers Estefania Azevedo and Whitnei Smith.
š Simple but effective: The microbiome diet emphasizes fiber-rich vegetables, berries, fermented foods, and probiotics to feed the good bacteria, while excluding sugar to āstarveā the bad.
Todayās top reads
LONG-LEVITY
Leaving the peanut-free table

image credit: freepik
š„ Peanut butter is my favorite food group. Unfortunately, many people with debilitating peanut allergies cannot have it (or even go near it).
However, a recent NIH study shows that immunotherapy enables children with a peanut allergy to eat peanut butter without an allergic reaction.
The peanut butter test: Children in the test group were initially able to tolerate peanut butter at a dose of 1/8 teaspoon (this is considered high threshold). They increases the dose every eight weeks to eventually work toward three whole tablespoons (9 grams).
Nearly 86% of children in the test group continued to tolerate nine grams, even after cutting peanut butter out of their diet for a short time. In other words, this new-found peanut tolerance is generally long-lasting.
Researchers are excited to see if this method can work with other food allergens.
Note, they did NOT study children with a more severe or life-threatening allergy.
LIVELONG+

šREAD: Breath: The New Science of a Lost Art by James Nester. You are probably breathing wrong, but your life depends on breathing right.
š§ LISTEN: Outdoor living for longevity! Outside Interactive Founder and CEO Robin Thurston talks about the revolution in outdoors, technology, and health.
š½ļø TASTE: Protein-packed guacamole from longevity dietician @Cookingforpeanuts.
š¬ SHARE: Know someone whoās passionate about living longer and healthier? Share this newsletter to spread the knowledge.
š³ GROW: Donāt forget to grab your ticket to the Livelong ExperienceāMarch 28-29āwe are so excited to meet you and dive deeper into longevity together.
š¦ WISDOM FOR LIFE
Let February be a reminder to cherish the ones you love
-Journey Journal
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