Takeaways:

  • Prolonged sitting harms metabolic and cardiovascular health, even in active people.

  • The soleus push-up (a seated calf raise) significantly improves post-meal blood glucose and insulin response in small controlled trials.

  • The calves play an underappreciated role in vascular, metabolic, and functional health.

"Sitting too much is not the same as exercising too little," says human performance researcher Marc T. Hamilton of the University of Houston. We often assume the solution to modern metabolic disease is sit less and move more. 💃 Both are true, but there’s nuance.

In 2022, Hamilton's lab identified an exercise approach to activate one of the body’s most metabolically unique muscles — the soleus, a small calf muscle that accounts for about 1% of body weight.

It’s nothing short of a contradiction. Smaller than most muscles, the soleus is somehow more metabolically active, and the most effective way to target it? Sitting. 🪑 What can the soleus pushup do for you?

If this topic resonates with you, we need you at the Livelong Women’s Health Summit.

With two days of practical science, strategies, and interventions, this experience can help you feel more energetic, strong, and healthy.

You’ll feel different after hearing talks from Dr. Mary Claire Haver, author of The New Menopause, and Dr. Stacy Sims.

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🥼 The soleus study that started it all

In the Hamilton study (published in the journal iScience), 25 participants did continuous soleus push-ups while researchers tracked metabolism. Basically, they just did a ton of seated calf raises. 

Compared to sitting still:

  • 52% better post-meal blood sugar: More stable energy and mood.

  • 60% lower insulin: Meaning less needed to clear glucose from the bloodstream, keeping metabolism activated.

  • 🦵Legs barely fatigued: Unlike hamstrings or arms, the soleus can go hours without fatiguing.

A 2025 Diabetes & Metabolic Syndrome review found that 3 minutes of soleus pushups after 30 minutes of sitting cut insulin spikes 26% in at-risk adults. 

Early trials suggest that 8 minutes of soleus pushups can even support patients with existing heart disease, reducing harmful LDL cholesterol while having anti-inflammatory effects on the cardiovascular system.

These studies are outliers, though, pitching sitting as part of the solution to metabolic diseases. Sitting is usually linked to poorer metabolic health and aging.

💺 The science of sitting, and the soleus

Americans sit 10 hours daily, on average, according to the CDC/NHANES, and it’s a habit that can wreak havoc on metabolic and functional health, contributing to obesity, diabetes, heart disease, dementia, joint pain, inflammation, arthritis, and frailty. 

Aging can worsen the risk, with an estimated 80% of adults aged 65+ will develop at least one chronic condition. 

Movement offsets metabolic decline, but even walking 🚶‍♀ (top research-backed longevity activity) activates the soleus less than the pushup.

In fact, the soleus pushup is the "exact opposite of walking,” Hamilton tells University of Houston reporters.

  • While walking engages more of the visible calf muscle, the gastrocnemius, the pushup isolates the soleus to concentrate the benefits in a single movement.

And, while most muscles are fueled by glycogen—a form of glucose stored in the liver and muscles 💪—the soleus is not. 

  • The soleus is 88% endurance (slow-twitch) fibers. In a process called oxidative metabolism, these fibers recruit oxygen to burn fat and glucose directly from the bloodstream—rather than dipping into glycogen reserves.

  • That means they can work for hours without fatiguingjust like a marathon runner 🏃

Training slow-twitch (endurance) fibers may be associated with muscle preservation, reduced inflammation, and better mitochondrial function in mice in aging studies, with mitochondria being a key hallmark of longevity.

The soleus: Part of your ‘second heart’

The soleus is one of two major muscles in the calves, considered the body's "second heart" for its ability to pump blood back toward the heart, aiding in circulatory and vascular function. 

💫 The calves are linked to healthy aging and longevity in other ways, too:

  • Lower frailty risk

  • Fewer falls and fractures

  • Improved function in older adults

  • Dementia risk (Calf circumference is linked to dementia risk)

Japan’s national fitness guidelines even feature calf raises among 3 core longevity exercises.

This is not an excuse to sit more… Sitting is a metabolic risk, even with soleus pushups in your back pocket.

More than 90 minutes without moving promotes visceral fat accumulation — an inflammatory fat tied to brain fog, diabetes, and heart disease. 

There are a few other limitations.

Most soleus research is done in small trials, often with sedentary or metabolically-compromised adults. So the benefits for healthy adults need more data. 

It also can’t rival the decades of evidence for cardiorespiratory fitness, muscle mass, and general movement in preventing heart attack, dementia, and death.

How to do a soleup pushup

Sit with feet flat. Lift your heels while keeping the balls of your feet down. Lower slowly down. Repeat.

That’s it! 🥳

Time: Often done 30–60 minutes after eating, it’s been studied for 3 minutes up to 3 hours under supervision. For daily use, start with 3 minutes after a meal, or every 30 minutes of sitting, and build from there.

For broader calf health: add standing calf raises and heel drops.
Aim for 3 sets of 10–20 reps, 3–5 days per week

🗝 Key takeaway

At 1% of your body weight, the soleus is small but metabolically mighty. Whether it’s 3 hours or 3 minutes, strategically adding this exercise to your day may meaningfully improve blood sugar and metabolic health, one heel raise at a time.

What’s New at Livelong (and How to Get Involved) …

✉️ Ambassador call-out! We’re looking for ambassadors for the Livelong Women’s Health Summit. Head to https://livelongmedia.com/ambassadors to learn how you can get involved and make a difference.

👉 Join the Livelong Women’s Circle: Connect with like-minded individuals taking control of their health journey. 💬🌱

Market booth and sponsorships: Meet your clients where they are at the Livelong Women’s Health Summit, April 17-18, San Francisco. See Media Kit.

Ask LIV: We’ve added an AI-powered tool that answers your health and longevity questions.


The bathroom clue that could save your heart” With Aleece Fosnight

This week’s episode is exclusively available on the Livelong PodcastTM.

Poll response

We asked, you answered: Would you give up salting food to add 2 years to your life?

  • Yes, and I’m not salty about it (61%)

  • Maybe, if it didn’t ruin the taste (15%)

  • No, I don’t think all salt is bad (13%)

“It’s more difficult when your spouse also cooks meals and thinks they are 'just adding a little salt…’” This is so relatable. Whether it’s a spouse, friend, or restaurant, navigating sodium intake when others season the food is tough! So, what can you control? Using the salt shaker.

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The information provided about wellness and health is for general informational and educational purposes only. We are not licensed medical professionals, and the content here should not be considered medical advice. Talk to a doctor before trying any of these suggestions.

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