🙌 Happy Friday! 

Ozempic (semaglutide) has biohackers and longevity scientists openly debating its anti-aging potential, while restaurants are indirectly joining the conversation more practically. Across the industry, restaurants are shrinking portion sizes or adding protein to accommodate changing appetites. 

This week: ‘Ozempic face,’ panda food, rare healthy sugar, and bringing it back to the basics.

Quick Poll

Which under-discussed downstream effect of Ozempic interests you most?

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Spotlight

🔎 Google searches for ‘Ozempic face’ rise 4,600%

As Ozempic use rises, so do concerns about looking older.

Image credit: Northwell.edu

GLP-1 drugs have helped millions lose weight and improve metabolic health.

With these benefits comes a surging interest in “Ozempic face,” face volume loss linked to rapid weight loss, with one Google Trends report showing a 4,600% rise in searches for the term. 📈

Related searches are growing, too:

  • “What is Ozempic face?” rose 2,900%

  • “Plastic surgeons Ozempic face” rose 3,700%

  • “Ozempic face before and after” rose 2,950%

Why this matters: Popular weight loss drugs may lead to a visibly older appearance, which is a growing concern.

“Patients with significant weight loss may look up to 5 years older than peers without such weight changes,” based on the ASJ review.

A 2025 review in Aesthetic Surgery Journal shows that searches for ‘Ozempic face’ now outnumber searches for ‘Ozempic side effects.🙁

  • The problem: Rapid weight loss can reduce fat everywhere. This is noticeable in the face (especially the cheek and eye), and it can create a hollow look that accentuates an aged appearance, writes Dermatology Times.

🖼 Big picture: Side profile > side effects

Aesthetics appears to be as great a concern as any other side effect.

  • Experts advise that people on GLP-1s aim for slower weight loss, stay hydrated, and wear sunscreen. 🫗

  • Dermal fillers and surgical options can add face volume, while microneedling and infrared light may show promise for skin quality. 🥼

The Livelong Women’s Health Summit

At the Livelong Women’s Health Summit, hear from legendary actress and activist Jane Fonda, and longevity pioneers like Dr. Dean Ornish, Dr. Jessica Shepherd, and Dr. Vonda Wright—among more than 75 expert voices shaping the science and lived experience of aging well. Use promo code ERIN for a discount on your ticket.

Wellness Watch

🎍 Is bamboo the superfood you haven’t tried?

You might want to consider adding Panda food to your pantry.

In the first comprehensive academic review of edible bamboo, researchers from Anglia Ruskin University have identified a new food with “superfood” potential: Bamboo shoots.

Antioxidant-rich and anti-inflammatory, they may support healthy aging, blood sugar control, and heart health. 🩺

🐼 How bamboo might improve aging

Bamboo shoots, the tender young edible sprouts, are a familiar Asian staple. Similar to broccoli sprouts and pea sprouts, they are a low-calorie and nutrient-dense food, packed with protein, vitamins, and minerals:

  • 🦠 Gut-supporting fiber: Bamboo feeds good gut bacteria and reduces inflammation. 

  • Carcinogen-reducing effects: May reduce acrylamide, a potential carcinogen created when cooking certain foods at high heat.

  • Metabolic support: Human studies show that bamboo regulates blood sugar and reduces unhealthy fat buildup that can lead to heart disease and aging

Don’t get bamboozled: Raw bamboo is toxic . Always boil it or buy it pre-cooked. And while the evidence is convincing, large human trials are limited. 

Key takeaway: Bamboo isn’t a proven superfood, yet. It is a fiber-filled, antioxidant-rich, and inexpensive food that could support energy, metabolism, and resilience against disease.

In Other News

🧁 Engineering a rare sugar substitute

All the sweetness, with fewer risks.

Researchers at Tufts University developed a cost-efficient way to produce tagatose, a rare sugar substitute that tastes like table sugar (sucralose) without the metabolic tsunami. The findings were published in Cell Reports Physical Science. 

Tagatose occurs naturally in small quantities in milk, dairy, and some fruits, but traditionally, it’s been too expensive to produce in bulk. In this study, scientists engineered bacteria to efficiently convert glucose into tagatose at low cost, while preserving its health benefits.

  • 🦷 Better oral health: May inhibit cavity-causing bacteria. 

  • 60% fewer calories than table sugar, with less risk of causing obesity.

  • 🩸 Minimal blood sugar spike: The gut ferments most of it.

  • 🍳 Cooks like sugar! Performs well in baking, with a similar mouthfeel.

A tastier future: As demand for no- and low-sugar is booming, this breakthrough could mark a new era of sweeter, healthier aging. 🍰🍩 🍪

JOIN The Women’s Livelong Lab (WLL): It’s free to join and easy to use, and we’d love to see you there. 😊 Reach out to [email protected] with any questions.

This week’s highlights

QUICK READS

  • 💀 ‘Are you dead yet?’ The morbid app that people in China are using to confirm they’re still alive.

  • 🧬 To EDEN: AI is learning the language of biology with trillions of DNA data points.

  • 🧠 Saffron keeps your brain on: A Nutrients study shows saffron extract could be a potent nutraceutical for memory, anxiety, and healthy aging.

LONG-LEVITY:

Why your brain loves ‘easy’ beauty

And how it might help us age gracefully.

We’re wired to take the easy road. According to a new study in PNAS Nexus, this preference has made us evolve to find beauty in ‘average’ things. 🥹

👍This ‘basic’ instinct may be surprisingly good for you.

Familiar, unstimulating, and low-contrast scenes like blurry mountains and blue skies don’t require as much brain power. This lets your mind take ‘cognitive shortcuts’ and relax.

The benefits: Easy and expansive scenes may lower stress by conserving brain energy. 🧘‍♀ Scenic beauty can also improve mood, attention, focus, decision-making, and cognition linked to healthier aging.

  • Faux pas: Humans tend to prefer ‘average’-looking faces too, but that’s familiarity and not truly indicative of beauty.

🛣 Gaze at the familiar every once in a while—whether it’s a blue sky or a loved one’s eyes. They are beautiful, and your brain will thank you.

Want to get involved in the Livelong Women’s Health Summit?!

🛍️ Vendors have the opportunity to connect with your audience at the Livelong Women’s Health Summit, April 17–18 in San Francisco. See the media kit for more information.

💫 If you’re passionate about women’s health and longevity and want to help spread the word about the event, you can join us as an Ambassador! Check out the details and reach out to [email protected] with any questions.

Poll response

We asked: How do you think about surgery as you age?

40% call it a last resort, but many also support it… so long as there’s strong proof it works. The number one surgery in adults 50+ is cataract removal to restore vision. Low-risk and high-reward, surgery sometimes can make the world brighter.

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The information provided about wellness and health is for general informational and educational purposes only. We are not licensed medical professionals, and the content here should not be considered medical advice. Talk to a doctor before trying any of these suggestions.

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