

🙌 Happy Friday!
It’s American Heart Month ❤ , and we want to start with something to smile about. :) Studies show that laughter can reduce your risk of a heart attack, both oxygenating your cells and improving blood flow – it delivers up to 20% more blood to the rest of your body!
When was the last time you really laughed? For those of you who need a little help, there’s always laughter yoga. 😂 🧘
This week: New heart attack insights, science confirms a two-day oatmeal ‘reset’ lowers cholesterol, and Sweden’s adorable “friendcare” initiative…
Quick Poll
Which heart-health habit do you think has the biggest impact on long-term longevity?
Spotlight


🧠 Could brain signals make heart attacks deadlier?
What if heart attack damage spreads beyond the heart?

Treating a heart attack usually involves knives, needles, and valves to open blockages and repair the heart. It’s risky, stressful, and might not stop long-term damage. 🔪 💉
Now, a mouse study from the University of California, San Diego, published in the journal Cell, shows heart attacks are an interconnected problem between the heart, brain, and immune system. And that conversation could be making things worse.
We’re flipping the switch on heart attack research,” says author Vineet Augustine in a UCSD article. It’s an insight that could lead to therapies that don’t even target the heart at all.
Here’s how it works: The conversation between the heart, brain, and immune system plays a role in how a heart attack unfolds. When a heart attack happens:
♥ The heart sends an injury signal to the brain
🧠 The brain activates the immune system
🔛 The immune system turns on (i.e., inflammation)
That inflammation doesn’t fix the injury, though. It spreads it. I think about it like rubbing a stain deeper into a white shirt.
But blocking communication between the heart and brain “stops the spread of the disease,” Augustine says, which significantly reduces the damage.
Why this matters: Brain-driven inflammation may be worsening heart attack damage. The future of heart protection could be as much about stopping the conversation between the heart and brain as it is about reopening a blocked artery ‼
See you in San Francisco at The Livelong Women’s Health Summit
Join us for the Livelong Women’s Health Summit on April 17-18, where you’ll learn from 75+ globally-recognized health leaders about simple, science-backed strategies to tackle menopause symptoms, get strong, supplement right, and take control of your biology. Use promo code ERIN to get your ticket.
Wellness Watch


🥣 A 2-day oatmeal “reset” cuts cholesterol for weeks
Oatmeal is already a heart-healthy breakfast. An “oat-reset” might be better.

A new study published in Nature Communications found that just 48 hours on an oatmeal-based diet lowered LDL (‘bad’) cholesterol by ⬇ 10%. Even more surprising is that cholesterol stayed lower for weeks after the reset ended.
Researchers at the University of Bonn, Germany, compared different approaches to reducing cholesterol in people with metabolic syndrome.
1⃣ Oatmeal diet: Two days of 300 grams of oats per day (about 3+ cups), plus calorie restriction and a small amount of fruits and vegetables.
2⃣ Calorie reduction only: Two days of reduced calories, no oats.
3️⃣ Moderate oat intake: One oat-based meal per day for six weeks.
The short high-dose, oatmeal diet had the strongest impact, while moderate intake only produced a small LDL drop. Calorie reduction was insignificant.
Why it works
Oats feed beneficial gut bacteria 🦠 and contain ferulic acid, a compound that helps the gut produce metabolites that lower cholesterol and other disease risks.
And what’s good for the gut is good for cholesterol. The sudden and dramatic bump in oats is believed to have positively shifted the microbiome.
✅ Takeaway
Increasing fiber intake from oats, whole grains, fruits, vegetables, and fermented foods supports a healthy gut microbiome and benefits cholesterol, metabolism, heart health, and aging. 🌾 🥑
In Other News

📖 Creating DNA: The new technology that could revolutionize precision medicine
If humans are a story, DNA is the words that bring our story to life. For a long time, we've only been able to create 'short stories' using short DNA sequences…
Now, Caltech researchers have pioneered Sidewinder, a technology that can build long, perfect sequences of DNA. 🧬 With AI at the helm of designing these sequences, it could revolutionize longevity research and precision medicine.
Like a book, Sidewinder gives DNA sequences ‘page numbers’, then strings them together to create long chains of functional DNA.
This DNA can be used to create genes, genomes, and gene clusters that “complete the book of life," says Caltech's Kaihang Wang, an assistant professor of biology and biological engineering.
🖼 Big picture: This technology has the potential to create new gene therapies, vaccines, and custom biology with implications for extending lifespan and precision medicines, and creating research breakthroughs.
JOIN The Women’s Livelong Lab (WLL): It’s free to join and easy to use, and we’d love to see you there. 😊 Reach out to [email protected] with any questions.
✨ This week’s highlights
QUICK READS
🍊 Less is more: A dietitian lists four popular supplements that might not actually support healthy aging.
🥛 Full-fat: A 25-year study from Sweden found that full-fat dairy surprisingly reduces the risk of all-cause dementia more than low-fat dairy.
🧬 22 risky genes: Researchers discover 22 genes that increase the risk of heart disease, cancer, and other long-term chronic conditions.
Ask LIV: You’re in LUCK! We have a new AI tool that can answer your longevity questions. Ask your first question.
LONG-LEVITY

🤝 Sweden’s ‘friendcare’ experiment
Building relationships pays more than you think.

The Swedish pharmacy chain Apotek Hjärtat is paying select employees to make time for friendship.
In a novel year-long program called ‘friendcare’ (vänvård), select employees are getting paid time during the workday to nurture existing relationships and form new connections in an effort to combat loneliness. 🫂
This goes beyond workplace wellness…
Harvard’s 85-year happiness study 😄 shows that strong relationships are the biggest predictor of longevity and life satisfaction.
Loneliness, in contrast, is linked to higher risks of heart disease, depression, and dementia.
As the initiative gains traction, other companies are testing wellness grants, cultural outings, paid massages, and “wellness hours,” incentivizing habits that promote healthy aging.
Friendcare exemplifies how a little push can create positive ➕ changes that support living happier, healthier lives.
You can practice your own version of friendcare today. Start by:
☕ Scheduling a weekly social event
📞 Replace scroll breaks with friendly check-ins
🧑🤝🧑 Treat relationships as a skill. You need to practice to get a better result

Want to get involved in the Livelong Women’s Health Summit?!
🛍️ Vendors have the opportunity to connect with your audience at the Livelong Women’s Health Summit, April 17–18 in San Francisco. See the media kit for more information.
💫 If you’re passionate about women’s health and longevity and want to help spread the word about the event, you can join us as an Ambassador! Check out the details and reach out to [email protected] with any questions.
Poll response
We asked: Do you choose organic produce?
Choose organic when possible (38%)
Choose organic when it’s affordable (27%)
Organic fruits and veggies aren’t treated with synthetic pesticides or GMOs and are grown more sustainably. That said, research shows organic isn’t necessarily healthier than conventional. As the Mayo Clinic puts it: “The best choice… is the one that puts the highest amount and variety of fruits, vegetables, and grains in the diet.”

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The information provided about wellness and health is for general informational and educational purposes only. We are not licensed medical professionals, and the content here should not be considered medical advice. Talk to a doctor before trying any of these suggestions.


