
Livelong Weekend Pulse
Your weekly snapshot of the breakthroughs shaping how we live longer and better.
Know Your DNA Patterns to Prevent Disease
Imagine spotting a heart attack, cancer, or dementia risk before any damage is ever done.
That’s the vision of Dr. Wei-Wu He, Executive Chairman of Human Longevity, Inc. Originally founded by genome pioneer Craig Venter, Human Longevity is one of the first companies to build “data-driven, preventative medicine,” combining genome, blood, advanced imaging, and AI to create a personal risk map of the diseases that are most threatening to you.
Most Americans don’t die of old age. They die of preventable disease. Our job is to make sure you don’t.
Why this matters now
The 90% problem: Heart disease, cancer, dementia, diabetes, and accidents account for nearly all US deaths. Most can be delayed or avoided if caught early.
Affordable, effective prevention: Sequencing your genome once costs about $1,000 today (down from $10,000 a decade ago) and could guide your health decisions for a lifetime.
Early action saves lives: Stage 1 breast cancer has a 99.7% 5-year survival rate. By stage 4, survival drops below 30%. The difference isn’t treatment, it’s timing.
The longevity leap
Dr. He envisions a future where:
Whole genome sequencing becomes as routine as a cholesterol check.
AI models flag your personal weak spots years before symptoms show.
Regenerative medicine (stem cells, organ replacement, even rejuvenated skin) adds decades of healthy life.
Metabolic balance is a priority, supported by interventions like GLP-1 drugs for obesity, which can extend healthspan for millions.
The takeaway? We have the technology to make living to age 90 or 100 in good health the new normal. If we stop waiting for disease to strike and start using the tools already at our fingertips, we could extend healthspan and lifespan for generations to come.
What else do you need to know about longevity this week?
🧑🤝🧑 Why Your 25-Year-Old Friend Might Be Your Best Anti-Aging Secret
A large-scale study suggests intergenerational friendships boost longevity by increasing physical activity, mental stimulation, and emotional resilience. The effect works both ways—older adults gain energy while younger ones gain wisdom.
👉 Explore the research
🦠 The Gum Disease-Alzheimer's Link Gets Serious
The NIH is funding a major trial testing whether targeting Porphyromonas gingivalis—bacteria from gum disease found in Alzheimer's brains—can slow cognitive decline. If proven, your dental hygiene routine becomes brain protection.
👉 Read the details
💊 Amazon Pharmacy’s Bold Play for Your Medicine Cabinet
Since 2020, Amazon Pharmacy has been applying its retail mastery to medications—offering same-day delivery, automatic refills, and simplified pricing for everything from insulin to GLP-1s. Their PillPack service delivers your daily medications in date-and-time labeled packets, eliminating the pill bottle shuffle.
👉 Explore how it works
🇯🇵 Japan's Longevity Success Story Has a Problem
Japan leads the world in life expectancy, but its shrinking birth rate creates a crisis: can fewer young people support more elderly citizens? The answer affects longevity strategies worldwide.
👉 Read the analysis
🎥 Dr. Vonda Wright: "Why I Skip Morning Workouts"
"I'm not going to waste that brain energy on physical activity when I need it for deep work. After 2 PM I could build you a house, but if I'm going to write a book, it's going to be early."
Turns out she might be onto something—new research suggests that afternoon workouts may offer greater longevity benefits than morning sessions. But Dr. Wright's real message? Know your natural rhythms and work with them, not against them.
📊 COMMUNITY POLL
Last week, 40% of you said you currently need/receive care, and 27% are caregivers. This week:
When do you typically workout?
Have a great weekend,

Erin is the Senior Editor at Livelong Media, where she explores the intersection of health, science, and the human experience.
The information provided about wellness and health is for general informational and educational purposes only. We are not licensed medical professionals, and the content here should not be considered medical advice. Talk to a doctor before trying any of these suggestions.
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