The Livelong Newsletter

Issue 77 | September 26, 2025

Sharing insights to guide your health, wellness, and longevity journey.

Happy Friday! In this week’s Wellness Watch, we’re exploring consumer health with Amazon Pharmacy. Consumer wellness isn’t just supplements and prescriptions though. It’s also pantry staples.

Case in point: I came across Sport Pasta, an $8.00 heirloom Italian pasta (actually more expensive than some medications) which promises easier digestion, 18 grams of protein, and 10 grams of fiber per serving. I love pasta, but I’ll probably wait until it goes on sale.

Let’s go! 🚶‍♀️

This week:

  • 🦷  Mouth bacteria are linked to Alzheimer's disease

  • 💊 Alexa, get me my prescriptions

  • 🏃 The new AI to predict disease risk

  • 📿 The crafty social activity for your brain, and beauty

👁️‍🗨️Spotlight

Could Mouth Bacteria Be Fueling Alzheimer’s?

created by Midjourney

The way to my heart is through my belly. 🧠 The way to my brain (and yours) could be through mouth bacteria.

A growing body of research suggests that a bacterium in the mouth called P. gingivalis could be a serious risk factor that fuels Alzheimer’s disease.

The Science

A cause of gum disease, P. gingivalis can infiltrate the brain and release toxic enzymes (gingipains) that trigger inflammation and brain injury. This cascade of inflammatory processes can cause the build up harmful brain proteins, classic hallmarks of Alzheimer’s.

In an effort to find more ways to treat the disease, the National Institute on Aging has granted nearly $50 million to fund a study of LHP588, a drug created by Lighthouse Pharmaceuticals to block the enzymes from creating neurotoxic inflammation.

  • In past studies, Alzheimer’s patients with P. gingivalis who received a similar drug experienced significantly slower cognitive decline.

Big picture 👉 With six million Americans living with Alzheimer’s, a complicated disease that still has no cure, understanding all risk factors could lead to preventative treatments that extend global health span.

Wellness Watch

Delivering a Different Pharmacy Experience

Alexa, refill my prescriptions.

created by Midjourney

Operating since 2020, Amazon Pharmacy was designed to make the pharmacy experience more easy and convenient than ever.

With transparent pricing, same-day delivery options, and affordable medications, from GLP-1s to insulin and supplements, Amazon is taking their retail playbook to the clinical space. 🚚

“We're very good at getting packages to your door,” Christina Smith, Senior Communications Manager at Amazon Pharmacy, tells Livelong. “We should be able to get medications to your door just as reliably.”

📦 Key features

PillPack is one of the most popular assets, offering pre-sorted daily packets of pills labeled by date and time. ”So you don’t juggle six pill bottles,”  she says.

Also included:

  • Autofill monthly: Fills/delivers medications automatically 🔄

  • Caregiver feature: Allows family and caregivers to manage patient prescriptions

  • 24/7 pharmacist chat service: Ask pharmacists questions or concerns anytime

  • Automatic manufacturer coupons 💸: offers lower-cost options for insulin, GLP-1s, and other life-saving drugs

  • Cash-pay alternatives: Transparent, up-front pricing

The future of pharmacy: Billions of healthcare dollars are spent on managing chronic conditions, but Christina hopes that younger, healthier customers could adopt the Pharmacy to get their products that support disease prevention, as much as those who use it for chronic conditions.🛡️

Note: Amazon Pharmacy does not prescribe orders or act as a replacement for the local pharmacy, Smith says. It also does not supply specialty medications, medical devices, or compound medications.

Sponsored by:
Codeage

Premium, high-quality products and supplements for your daily routine.

Nourish your body with the best of what nature and science offer. Codeage products are more than just formulas and supplements; they're a lifestyle choice. Shop here.

Top Story

AI forecasts your future health 🧑‍💻

What if a doctor could tell you not just what’s wrong today, but what might go wrong 20 years from now?

A new generative AI tool, Delphi-2M, can predict a person’s 20-year risk of 1,000+ diseases, according to a new paper in Nature. Delphi was trained on data from 403,000 people to learn how diseases progresses. In some cases, it can predict risks more accurately than blood-biomarker-based models, a popular method that uses blood to assess health. Researchers see AI’s potential for early predictions, helping more people get tests and proactive screenings to stay healthier, for longer. 

Quick Hits

  •  ​​🫐 Hunter-gatherer wisdom: Paleo diet is a fad. Here’s what we can learn from the world’s healthiest indigenous tribes, according to an anthropologist.  

  • 🔻Japan’s conundrum: Women make up 88% of Japan’s centenarians, but a declining birth rate poses a new emergency.

  • 🧠 Fat & your brain: BMI aside, fat distribution influences dementia risk. These are the riskiest types.

Long-levity

Beading Bars: A Bespoke New Social Hub

The crafty trend that creates beauty and supports social and mental health.

created by Midjourney

From 80-plus club nights to water-tasting bars, 💧traditional social spots are evolving. On our radar? Pop-up Beading Bars. These creative gatherings bring people together to make luxury and handcrafted jewelry, brooches, and charms.

Jewelry brand Don’t Let Disco, which offers the bespoke experience, calls beading bars a “collective creation” that taps into “the meditative process of making.”

The benefits: Participating in the arts can boost serotonin levels, reduce stress hormones, and make life feel fulfilling, according to psychologist Dr. Helen Keyes.

Try it! Bead Bar at Home

What you’ll need:

  • 🪞 Beads: Sophisticated stones, reclaimed materials, or rock-crystal that mimics their style

  • 👯 Friends: Connection and community make the experience

  • 🧵  Cord: Silk, leather, cotton, or hemp

🍹 BONUS: Mocktails! We recommend these mocktails from the Livelong experience.

This Week

Coming Soon: The Livelong Woman

We’re thrilled to introduce The Livelong Woman, an upcoming newsletter dedicated to women’s health and longevity.

Led by Editorial Director Rachel Lehmann-Haupt and writer Tiffany Nieslanik, The Livelong Women brings the science, strategies, and stories in women’s health and longevity. As part of the Livelong community, you’ll automatically start receiving it when we launch. 🚀

Longevity we’re loving 🗣️

  • Free diver exercises to breathe better: The lungs are a cornerstone of health. Learn how to optimize yours. Read more

  • The Millennial caregiver: One woman’s mission to help young caregivers balance life and caring for a loved one with dementia. Watch the episode

Until next time!

Erin is the Senior Editor at Livelong Media, where she explores the intersection of health, science, and the human experience.

Thanks for reading!

Let us know what you thought of today's newsletter so we can continue improving the experience for you.

Login or Subscribe to participate

- Always seek the advice of a physician or other qualified healthcare professional before starting any exercise, wellness, or health program. Nothing in our content, products or services should be considered, or used as a substitute for medical advice, diagnosis, or treatment. Livelong is a media company and not a medical provider. We try to give the most accurate possible, but sometimes information is subject to change.
- Please note: Some links in this newsletter are affiliate links, meaning we may earn a small commission if you decide to make a purchase through them. This helps us continue to bring you credible and actionable health and longevity insights at no extra cost to you. Thank you for your support!

Longevity Media LLC

Look good, feel better, live longer

Reply

or to participate

Keep Reading

No posts found