The Livelong Podcast

“You’re going to find this [estrogen] patch on my dead body.”

For Dr. Sophia Yen, a Stanford adolescent medicine specialist and the Pandia Health CEO and co-founder, hormone therapy isn’t a short-term treatment…it’s lifelong health insurance.

In this episode, Livelong’s Erin Hunter sits down with Yen for a deep dive into menopause, perimenopause, hormones, birth control, and how estrogen loss rewires the body, driving visceral fat gain, cardiovascular risk, bone loss, and metabolic dysfunction. Dr. Yen also challenges the playbook (such as the “10-year window” and compounded hormones) and argues that much of modern menopause care is based on outdated information, not current evidence.

They explore:

  • Why menopause triggers visceral fat, cholesterol spikes, and arterial stiffening (and why this isn’t just “aging”)

  • The case for lifelong hormone therapy

  • Why birth control is often the best treatment for perimenopause

  • The misunderstood “10-year window” for starting HRT

  • The overlooked role of metformin in midlife metabolism and diabetes prevention

  • Protein-forward diets and the 60–60–60 longevity rule

We hope this conversation helps you understand the role of hormones and move beyond symptom management.

Give us two days. Our 75+ experts will share knowledge for a lifetime of health

Dr. Natalie Crawford, Dr. Mark Hyman, and Jane Fonda are only some of the speakers who are coming to the Livelong Women’s Health Summit this April in San Francisco.

If you’ve been considering joining us, this is your moment.

Updates

  • Got questions about longevity? Try our new AI toolLIV,’ which analyzes hundreds of studies, articles, and podcasts to give you real science-backed knowledge on longevity science and healthy aging. Chat with her here.

  • Seeking ambassadors for LLWHS: Our Women’s Health Summit is quickly approaching, and we’re looking for ambassadors to be part of the mission! Learn about ambassador opportunities.

  • Read next: 😴 Ever wonder what happens when women don’t sleep enough? Science shows women pay a steeper price for poor sleep in multiple ways. Read more here.

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The information provided about wellness and health is for general informational and educational purposes only. We are not licensed medical professionals, and the content here should not be considered medical advice. Talk to a doctor before trying any of these suggestions.

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